Last Week in Medicine
by Stephen Jenkins, MD, Austin Rupp, MD
Wouldn't it be nice if someone reviewed all the latest internal medicine literature and distilled it into a brief podcast you could listen to on your way to work? Get updates from the New England Journal of Medicine, JAMA Network, Annals of Internal Medicine, Journal of Hospital Medicine, Journal of General Internal Medicine, Lancet and more.
Copyright: © 2023 Last Week in Medicine
Episodes
Early Vasopressors and Restrictive Fluids in Septic Shock (CLOVERS), Furosemide vs Torsemide in Heart Failure (TRANSFORM-HF), Aspirin vs Enoxaparin after Extremity Fracture (PREVENT CLOT), Haloperidol for ICU Delirium (AID-ICU)
51m · PublishedWe're back with Season 4! Sorry for the unplanned hiatus.
Today we talk about the CLOVERS trial, which tested the hypothesis that early vasopressors and restrictive fluid would be superior to liberal fluids plus rescue vasopressors. We also looked at the TRANSFORM-HF study, which compared torsemide and furosemide in congestive heart failure, the PREVENT CLOT study, which compared aspirin to enoxaparin for VTE prophylaxis after a traumatic fracture, and the AID-ICU study, which compared haloperidol to placebo in the treatment of ICU delirium.
CLOVERS trial
Torsemide vs Furosemide in CHF
Aspirin vs Enoxaparin for VTE ppx after Fracture
IV Haloperidol in ICU Delirium
We also quickly review some papers we missed in 2022:
Apixaban for VTE in ESRD
Acetazolamide for Congestive Heart Failure
Moderate or Aggressive IV Fluids for Pancreatitis
Perioperative Management of Anticoagulation
CRISTAL study (aspirin vs enoxaparin after TKA/THA)
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
Early Vasopressors and Restrictive Fluids in Septic Shock (CLOVERS), Furosemide vs Torsemide in Heart Failure (TRANSFORM-HF), Aspirin vs Enoxaparin after Extremity Fracture (PREVENT CLOT), Haloperidol for ICU Delirium (AID-ICU)
51m · PublishedWe're back with Season 4! Sorry for the unplanned hiatus.
Today we talk about the CLOVERS trial, which tested the hypothesis that early vasopressors and restrictive fluid would be superior to liberal fluids plus rescue vasopressors. We also looked at the TRANSFORM-HF study, which compared torsemide and furosemide in congestive heart failure, the PREVENT CLOT study, which compared aspirin to enoxaparin for VTE prophylaxis after a traumatic fracture, and the AID-ICU study, which compared haloperidol to placebo in the treatment of ICU delirium.
CLOVERS trial
Torsemide vs Furosemide in CHF
Aspirin vs Enoxaparin for VTE ppx after Fracture
IV Haloperidol in ICU Delirium
We also quickly review some papers we missed in 2022:
Apixaban for VTE in ESRD
Acetazolamide for Congestive Heart Failure
Moderate or Aggressive IV Fluids for Pancreatitis
Perioperative Management of Anticoagulation
CRISTAL study (aspirin vs enoxaparin after TKA/THA)
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
SGLT2 Inhibitors for Acute Heart Failure, SGLT2 Inhibitors vs Metformin, High Dose Dexamethasone for COVID-19 in ICU, Isolated Distal DVT, Monkeypox, Blood Donor Sex and Mortality, Outcomes in Surgeons Who Operate the Night Before
44m · PublishedToday we have a couple special guests under the age of 2. Birdie and Gus!
Do SGLT2 inhibitors improve diuresis in acute heart failure? Are they better than metformin for reducing cardiovascular mortality? Is high dose dexamethasone better than standard dose in ICU patients with COVID?
We also talk about outcomes in patients with isolated distal DVT compared to proximal DVT, a large case series of patients with monkeypox infection, blood donor outcomes and the outcomes for surgeons who operated the night before. Check it out!
SGLT2-Inhibitors for Acute Heart Failure
Cardiovascular Outcomes for SGLT-2 Inhibitors vs Metformin
COVIDICUS Trial
Isolated Distal DVT Outcomes
Monkeypox Case Series
Mortality in Patients Undergoing Blood Transfusion
Perioperative Outcomes for Surgeons Who Operated the Night Before
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
SGLT2 Inhibitors for Acute Heart Failure, SGLT2 Inhibitors vs Metformin, High Dose Dexamethasone for COVID-19 in ICU, Isolated Distal DVT, Monkeypox, Blood Donor Sex and Mortality, Outcomes in Surgeons Who Operate the Night Before
44m · PublishedToday we have a couple special guests under the age of 2. Birdie and Gus!
Do SGLT2 inhibitors improve diuresis in acute heart failure? Are they better than metformin for reducing cardiovascular mortality? Is high dose dexamethasone better than standard dose in ICU patients with COVID?
We also talk about outcomes in patients with isolated distal DVT compared to proximal DVT, a large case series of patients with monkeypox infection, blood donor outcomes and the outcomes for surgeons who operated the night before. Check it out!
SGLT2-Inhibitors for Acute Heart Failure
Cardiovascular Outcomes for SGLT-2 Inhibitors vs Metformin
COVIDICUS Trial
Isolated Distal DVT Outcomes
Monkeypox Case Series
Mortality in Patients Undergoing Blood Transfusion
Perioperative Outcomes for Surgeons Who Operated the Night Before
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
Restrictive Fluids in Septic Shock, Short vs Standard Antibiotics in Neutropenic Fever, IV Vitamin C for Septic Shock, Hospitalist Workload and Patient LOS, Fluid Bolus for Intubation, General Internist Practice Choices
54m · PublishedToday we are joined by Dr. Brian Locke to talk about multiple new critical care trials, including the CLASSIC trial of a restrictive vs standard fluid strategy, the LOVIT trial of vitamin C in septic shock, and the PREPARE-II trial of fluid bolus at the time of intubation to prevent cardiovascular collapse. We also look at whether 72 hours of antibiotics are safe in patients with neutropenic fever, whether hospitalist workload affects patient length of stay, and what kind of careers general internists are pursuing over the last decade.
Restrictive Fluids for Septic Shock
Short vs Standard Antibiotics for Neutropenic Fever
IV Vitamin C for Septic Shock
Vitamin C Meta-analysis
Hospitalist Workload and Patient Length of Stay
Fluid Bolus for Intubation
General Internist Practice Choices
Genetically Modified Porcine to Human Cardiac Xenotransplantation
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
Restrictive Fluids in Septic Shock, Short vs Standard Antibiotics in Neutropenic Fever, IV Vitamin C for Septic Shock, Hospitalist Workload and Patient LOS, Fluid Bolus for Intubation, General Internist Practice Choices
54m · PublishedToday we are joined by Dr. Brian Locke to talk about multiple new critical care trials, including the CLASSIC trial of a restrictive vs standard fluid strategy, the LOVIT trial of vitamin C in septic shock, and the PREPARE-II trial of fluid bolus at the time of intubation to prevent cardiovascular collapse. We also look at whether 72 hours of antibiotics are safe in patients with neutropenic fever, whether hospitalist workload affects patient length of stay, and what kind of careers general internists are pursuing over the last decade.
Restrictive Fluids for Septic Shock
Short vs Standard Antibiotics for Neutropenic Fever
IV Vitamin C for Septic Shock
Vitamin C Meta-analysis
Hospitalist Workload and Patient Length of Stay
Fluid Bolus for Intubation
General Internist Practice Choices
Genetically Modified Porcine to Human Cardiac Xenotransplantation
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
Inpatient Management of Opioid Use Disorder, Hep C Treatment in IVDU, Final SOLIDARITY Results for Remdesivir, TAVI for Moderate Risk Severe AS, Mediterranean Diet vs Low Fat Diet, Steroids for IgA Nephropathy, GLP-1s and Gallbladder Disease
58m · PublishedToday we had Dr. Patricia Liu to talk about a new study from Journal of Hospital Medicine on the management of opioid use disorder in the hospital. And then we got a little carried away covering way too many articles!
Inpatient Management of Opioid Use Disorder
Hepatitis C Care for People Who Inject Drugs
Final SOLIDARITY trial results for Remdesivir
TAVI for Moderate Risk Severe Aortic Stenosis
Mediterranean Diet vs Low Fat Diet for Secondary Prevention of CVD
Steroids for IgA Nephropathy
GLP-1 Agonists and Gallbladder Disease
Pig to Human Kidney Xenotransplantation
Aspirin for Primary Prevention of CVD
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
Inpatient Management of Opioid Use Disorder, Hep C Treatment in IVDU, Final SOLIDARITY Results for Remdesivir, TAVI for Moderate Risk Severe AS, Mediterranean Diet vs Low Fat Diet, Steroids for IgA Nephropathy, GLP-1s and Gallbladder Disease
58m · PublishedToday we had Dr. Patricia Liu to talk about a new study from Journal of Hospital Medicine on the management of opioid use disorder in the hospital. And then we got a little carried away covering way too many articles!
Inpatient Management of Opioid Use Disorder
Hepatitis C Care for People Who Inject Drugs
Final SOLIDARITY trial results for Remdesivir
TAVI for Moderate Risk Severe Aortic Stenosis
Mediterranean Diet vs Low Fat Diet for Secondary Prevention of CVD
Steroids for IgA Nephropathy
GLP-1 Agonists and Gallbladder Disease
Pig to Human Kidney Xenotransplantation
Aspirin for Primary Prevention of CVD
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
2022 AHA/ACC/HFSA Heart Failure Guidelines with Dr. James Fang, Guideline Committee Member
32m · PublishedToday, Dr. James Fang, Chief of Cardiovascular Medicine at the University of Utah, and AHA/ACC/HFSA Heart Failure Guideline Committee Member, joins us to talk about the new heart failure guidelines, published in April 2022. We talk about the new classifications, including HF with improved EF and HF with mildly reduced EF, and new recommendations for medical therapy for all the heart failure types. How do you start someone on GDMT? Who should get SGLT-2 inhibitors? How can we get more people on ARNIs? Dr. Fang provides lots of clinical pearls and practical wisdom for applying these new recommendations. Check it out!
2022 Heart Failure Guidelines
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
2022 AHA/ACC/HFSA Heart Failure Guidelines with Dr. James Fang, Guideline Committee Member
32m · PublishedToday, Dr. James Fang, Chief of Cardiovascular Medicine at the University of Utah, and AHA/ACC/HFSA Heart Failure Guideline Committee Member, joins us to talk about the new heart failure guidelines, published in April 2022. We talk about the new classifications, including HF with improved EF and HF with mildly reduced EF, and new recommendations for medical therapy for all the heart failure types. How do you start someone on GDMT? Who should get SGLT-2 inhibitors? How can we get more people on ARNIs? Dr. Fang provides lots of clinical pearls and practical wisdom for applying these new recommendations. Check it out!
2022 Heart Failure Guidelines
Music from Uppbeat (free for Creators!):
https://uppbeat.io/t/soundroll/dope
License code: NP8HLP5WKGKXFW2R
Last Week in Medicine has 114 episodes in total of non- explicit content. Total playtime is 82:09:28. The language of the podcast is English. This podcast has been added on November 27th 2022. It might contain more episodes than the ones shown here. It was last updated on May 10th, 2024 05:41.
