Evidence-Based Health Care

EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss menopause and hormone replacement therapy (HRT) In this episode EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss menopause and hormone replacement therapy (HRT). We hear from Dr. Elizabeth Spencer and Professor Carol Coupland, both of whom have conducted research on the risks of HRT using large databases, including the landmark million women's study. This podcast series on evidence in women's health is brought to you by the Centre for Evidence-Based Medicine and the postgraduate programme in evidence based health care. Dr. Anne-Marie Boylan, a senior researcher and lecturer in the programme, and Associate Professor Jamie Hartmann-Boyce, interview relevant experts discussing the strengths and limitations of different sources of evidence as they relate to women's health and considering their implications for future research. In this episode EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss menopause and hormone replacement therapy (HRT) with interviews from Dr. Elizabeth Spencer and Professor Carol Coupland, both of whom have conducted research on the risks of HRT using large databases, including the landmark million women's study.

EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss menopause and hormone replacement therapy (HRT) In this episode EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss menopause and hormone replacement therapy (HRT). We hear from Dr. Elizabeth Spencer and Professor Carol Coupland, both of whom have conducted research on the risks of HRT using large databases, including the landmark million women's study. This podcast series on evidence in women's health is brought to you by the Centre for Evidence-Based Medicine and the postgraduate programme in evidence based health care. Dr. Anne-Marie Boylan, a senior researcher and lecturer in the programme, and Associate Professor Jamie Hartmann-Boyce, interview relevant experts discussing the strengths and limitations of different sources of evidence as they relate to women's health and considering their implications for future research. In this episode EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss menopause and hormone replacement therapy (HRT) with interviews from Dr. Elizabeth Spencer and Professor Carol Coupland, both of whom have conducted research on the risks of HRT using large databases, including the landmark million women's study.

Dr Clare J Taylor, Academic GP, explores how we can use large, anonymised GP datasets to improve our understanding of heart failure management in primary care. Nearly all UK residents are registered with a general practice and data collected during routine consultations can be used by researchers to understand more about common diseases. Heart failure occurs when the heart has been damaged and is struggling to pump enough blood to meet the needs of the body. Patients can feel breathless, exhausted and have swollen legs but treatments to improve quality of life and outlook are available. In this lecture, Dr Taylor explores how we can use large, anonymised GP datasets to improve our understanding of heart failure management in primary care. With a focus on the patient throughout, she presents her recent work on heart failure diagnosis and survival to illustrate the power, and limitations, of using big GP data for research and to ultimately improve patient care. Part of the Evidence-Based Health Care programme. About the speaker: Dr Clare J Taylor is a Clinical Lecturer in the Nuffield Department of Primary Care Health Sciences. Her research explores heart failure in primary care using big data epidemiology, prospective studies, and qualitative work. The findings have been published in high-impact journals and informed national and European heart failure policy. Clare is also experienced in postgraduate teaching and doctoral supervision and was a member of the National Institute for Health and Care Excellence Chronic Heart Failure guideline committee. She also works as an NHS general practitioner.

In 2022 a Canadian population based retrospective cohort study hit the headlines in the U.K. by claiming that women were 32% more likely to die if operated on by a male surgeon. The study was led by Christopher Wallace who sought to examine the link between surgeon patient sex discordance and postoperative outcomes. Data was collected for over 1.3 million patients and nearly 3000 surgeons were included. It found that 14.9% of patients had one or more adverse postoperative outcome. But that worse outcomes were seen for female patients operated on by male surgeons, but not for males operated on by female surgeons. Together with Director of the Centre for Evidence-Based Medicine, Professor Carl Heneghan, and EBHC DPhil Director, Dr. Jamie Hartmann-Boyce, Dr. Anne Marie Boylan discusses what this means for women, the accuracy of the study and whether it has any relevance here in the U.K. They also speak to Emily McFadden, a Senior Statistical Epidemiologist here at Oxford, Sunil Patel, a Canadian surgeon completing his DPhil in evidence based healthcare and Sharon Dixon, a GP and academic who's researching women's health in the department.Together with Director of the Centre for Evidence-Based Medicine, Professor Carl Heneghan, and EBHC DPhil Director, Jamie Hartmann-Boyce, Dr. Anne Marie Boylan discusses what this means for women, the accuracy of the study and whether it has any relevance here in the U.K.

Dr Anthony Webster, University of Oxford gives a talk on combining mathematical modelling with big data statistics to distinguish between sporadic, late-onset, and multi-stage diseases. Dr Anthony Webster, a statistician at the University of Oxford gives a talk gives a talk on combining mathematical modelling with big data statistics to distinguish between diseases strongly linked to ageing and those that could potentially be avoided by making good choices throughout life.

Dr Gordon Guyatt provides a guest talk on how we should teach evidence-based medicine in the 21st century This free guest lecture is part of the Teaching Evidence-Based Practice module, part of the Oxford University Evidence-Based Health Care (EBHC) programme. About the speaker: Dr Gordon Guyatt is a Distinguished Professor in the Department of Clinical Epidemiology and Biostatistics, McMaster University and one of the founders of Evidence-Based Medicine. He has played a key role in over 30 major clinical studies (including both large-scale observational and randomized trials) and has extensive expertise in study methodology. As co-founder and co-chair of the GRADE working group, he has been intimately involved in the development and evolution of the GRADE approach. Questions? Please contact the Evidence-Based Health Care (EBHC) team by emailing: [email protected] To stay informed of programme news, including lectures and research news, sign up to the EBHC mailing list: https://conted.us6.list-manage.com/subscribe?u=b349338a9a&id=9769482733

Joanne Greenhalgh, Professor of Applied Social Research Methodology (University of Leeds) on the experiences of conducting a realist synthesis of the feedback of aggregated patient reported outcome measure (PROMs) data to improve patient care. Her talk addresses two methodological questions (1) how do you carry out a realist synthesis of an intervention when there's 'no evidence'? and (2) how can you deal with the complexity of ‘context’?

Dr Anne-Marie Boylan and Dr Laura Griffith, ​explore the value of qualitative health research and discuss what it's really like to undertake qualitative research. Qualitative research is a naturalistic mode of inquiry. It is used to answer a variety of research questions that have relevance to health policy and practice. In this podcast, Dr Anne-Marie Boylan, Director of the Postgraduate Certificate in Qualitative Health Research Methods at the University of Oxford, and Dr Laura Griffith, a former academic who now works in public health, explore the value of qualitative health research and discuss what it's really like to undertake qualitative research. Speaker biography Dr Laura Griffith completed her PhD in Anthropology about Motherhood in the East End in 2006 completing research in London and Bangladesh. During this time she also worked as a consultant and was the Chair of the Management Board for Sure Start and actively involved in other public health projects. From there she started as a Research Fellow in Warwick as the PI for a project investigating the experiences of minority ethnic populations of acute psychiatric services. Next was leading a project at Aston University about multi-professional team working in Mental Health teams, and from there she moved to the Health Experiences Research Group, University of Oxford, where she completed modules on psychosis, giving up smoking and experiences of ECT for the renowned healthtalk.org. She went on to lecture at the University of Birmingham in the sociology of health, and led the Health and Well-being stream in the Institute for Research into Superdiversity. At Birmingham she left the academic side of health research and moved into health consultancy - normally working with partners from the third sector. She now works in public health. Date: 18 May 2021

Professor Kamal Mahtani and David Nunan interview Professor Paul Glasziou, Director of the Institute for Evidence-Based Healthcare at Bond University, about his experience of leadership and his work in capacity building through teaching and supervision. Professor Kamal Mahtani is Director of the Evidence-Based Health Care Leadership programme and David Nunan is Director of the PGCert in Teaching EBHC

Professor Kamal Mahtani and David Nunan interview Professor Paul Glasziou, Director of the Institute for Evidence-Based Healthcare at Bond University, about his experience of leadership and his work in capacity building through teaching and supervision. Professor Kamal Mahtani is Director of the Evidence-Based Health Care Leadership programme and David Nunan is Director of the PGCert in Teaching EBHC