JAMA Clinical Reviews

The incidence of Cushing syndrome due to endogenous overproduction of cortisol is 2 to 8 people per million annually. JAMA Deputy Editor Mary M. McDermott, MD, discusses diagnosis, management, and treatment of this condition with authors Martin Reincke, MD, from University of Munich, and Maria Fleseriu, MD, from Oregon Health and Science University.

Related Content:

• Cushing Syndrome

The 2021 US maternal mortality rate is more than 10 times the rate of other high-income countries, according to a March 2023 CDC report. In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, is joined by Monica McLemore, PhD, MPH, RN, University of Washington, Audra Meadows, MD, MPH, UC San Diego, and Joia Crear-Perry, MD, founder and president of the National Birth Equity Collaborative, to discuss these concerning numbers and why preventable death rates are worsening in the US.

Related Content:

• Trends in State-Level Maternal Mortality by Racial and Ethnic Group in the United States
• Worsening US Maternal Death Rates
• US Maternal Mortality Is Unacceptably High, Unequal, and Getting Worse—What Can Be Done About It?
• Trends in Maternal Mortality and Severe Maternal Morbidity During Delivery-Related Hospitalizations in the United States, 2008 to 2021

Interview with Michael Silverstein, MD, MPH, USPSTF chair and coauthor of Screening for Depression and Suicide Risk in Adults, and Screening for Anxiety Disorders in Adults: US Preventive Services Task Force Recommendation Statements. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.

Related Content:

• Anxiety Screening
• Depression and Suicide Risk Screening
• Screening for Depression and Suicide Risk in Adults
• Screening for Anxiety Disorders in Adults
• Screening for Depression and Suicide Risk in Adults
• Screening for Anxiety Disorders in Adults
• Are There Reasons to Fear Anxiety Screening?
• Reframing the Key Questions Regarding Screening for Suicide Risk

JAMA Senior Editor Kristin Walter, MD, MS, speaks with Fernando Zampieri, MD, PhD, assistant professor in the Department of Critical Care Medicine at the University of Alberta in Alberta, Canada, about fluid therapy in critically ill adults with sepsis.

Related Content:

• Fluid Therapy for Critically Ill Adults With Sepsis

Transgender and gender diverse persons may desire gender-affirming medical and surgical treatment that can mitigate psychologic distress and reduce suicide risk. JAMA Associate Editor David L. Simel, MD, MHS, speaks with Andrew M. Davis, MD, MPH, University of Chicago, and Tonia Poteat, PhD, PA-C, MPH, University of North Carolina, Chapel Hill, about the Standards of Care for the Health of Transgender and Gender Diverse People, Version 8 guidelines.

Related Content:

• Standards of Care for Transgender and Gender Diverse People

Cirrhosis affects approximately 2.2 million adults in the US, and the annual age-adjusted mortality of cirrhosis has increased from 2010 to 2021. JAMA Senior Editor Karen E. Lasser, MD, MPH, and Elliot B. Tapper, MD, from the University of Michigan, discuss the diagnostic workup and evidence-based therapies for cirrhosis.

Related Content:

• Diagnosis and Management of Cirrhosis and Its Complications

Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.

Related Content:

• Screening for Latent Tuberculosis Infection in Adults
• Screening for Latent Tuberculosis Infection Among Non–US-Born Adults in the US
• Screening for Latent Tuberculosis Infection in Adults
• Screening for Latent Tuberculosis

Interview with Katrina E. Donahue, MD, MPH, USPSTF member and coauthor of Screening for Skin Cancer: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.

Related Content:

• Skin Cancer Screening
• Screening and Prevention of Skin Cancer
• Screening for Skin Cancer
• What Is Mohs Surgery?
• Skin Cancer Screening

One in 3 adults in the US has prediabetes. JAMA Associate Editor David L. Simel, MD, interviews Samuel Dagogo-Jack, MD, who is the chief of the Division of Endocrinology, Diabetes, and Metabolism at the University of Tennessee, about the diagnosis, screening, complications, lifestyle interventions, and medications for prediabetes.

Related Content:

• Diagnosis and Management of Prediabetes

Chronic lymphocytic leukemia (CLL) affects more than 200 000 people and is associated with >4000 deaths in the US annually. Many people have asymptomatic disease and can be monitored without treatment for long periods. In this podcast, author Mazyar Shadman, MD, MPH, from the University of Washington, Seattle, joins JAMA Deputy Editor Mary M. McDermott, MD, in a discussion about diagnosis and management of CLL.

Related Content:

• Diagnosis and Treatment of Chronic Lymphocytic Leukemia