Thyroid Mystery Solved: Hashimoto's and Hypothyroidism Revealed

The Case: 

• Donna has had hypothyroidism for 10 years
• Medication helped at first but lately, she’s experiencing fatigue and weight gain. 
• She was finally diagnosed with Hashimoto's which sent her on a Google frenzy and left her overwhelmed by information. 
• She’s got 4 kids, a full-time job, and is trying to manage Hashimoto’s with diet, exercise, and supplements - it's all too stressful. 

When I met Donna and heard about her busy life and her health struggles, I knew the two things were connected. She was doing a lot right by supporting her nervous system and immune system through diet, exercise, and supplements but in truth, they were no match for the stress she was under. Taking care of herself became the straw that broke the stress-camel’s back. 

I knew exactly where to look to help her solve her mystery. 

The Stress of ‘Never Enough Time’

One of the greatest challenges we face in our lives is managing our time effectively. It often feels like there are never enough hours in a day to accomplish everything we need to do. That's why I was thrilled to have Megan Sumrell, a time management expert, on this episode of Health Mysteries Solved. The first thing we tackled is the concept that there is never enough time in the day. 

Megan believes that there is a lot at play here. While many people rush to blame inadequate time planning for their unfinished tasks, our present-day world presents distinct challenges compared to the past. The expectations we impose on ourselves, as well as those imposed by others, have significantly evolved over the years. Looking back on her own journey, Megan acknowledges the tremendous increase in the number of responsibilities she now juggles compared to 15 years ago. 

To overcome this hurdle, Megan suggests that we find a balance between the influx of tasks and our capacity to handle them. It's crucial to reassess how we plan and manage our time, distinguishing between what is realistically achievable and what is not.

Why Managing Tasks Can Be Challenging in Today's World

Megan sheds light on two primary reasons that our task lists never seem to get done. First, she emphasizes the onslaught of distractions, particularly in the form of technology and all of these beeps, bings, and message notifications. She reminds us that, while technology has its benefits, if we don't learn to control it, it can easily control us. Additionally, the instant gratification culture we live in contributes to the perception that we have more to do, even if it's not the case. 

The second reason Megan highlights is the "just in time living" mindset many people operate in, where they only focus on their daily to-do list. Without systems in place to accommodate unforeseen events or changes, any disruption can lead to a cascade of delays and overwhelm.

This was exactly Donna's experience. She found herself buried under an ever-growing pile of to-do lists. Interestingly, Megan challenges the traditional notion of relying solely on to-do lists. While they have their time and place, she doesn't recommend solely depending on them. Megan acknowledges the satisfaction of checking off tasks but suggests that creating a list just to check it off may not be the most effective approach.

Transforming a Task List into an Effective Plan

Megan emphasizes the crucial distinction between a task list and a plan. While a traditional to-do list may contain all the tasks we need to accomplish, it lacks the essential elements of when and how long each task will take. Megan draws an analogy by comparing it to a shopping or grocery list without knowing how much money you have. Similarly, without turning our task list into a plan, we risk over-committing ourselves and not considering the feasibility or efficiency of our tasks.

Megan highlights the importance of budgeting our time just as we would money. By incorporating time constraints and prioritization into our planning process, we can make more informed choices about what tasks to tackle and when. This approach allows us to maximize efficiency, consolidate errands, and focus on what truly matters. Without this level of organization and prioritization, we may find ourselves perpetually trapped on a hamster wheel, feeling busy but not truly productive. And that is stress-inducing!

Mastering Prioritization and Overcoming Overwhelm

Understanding how to prioritize tasks can be challenging, especially when dealing with health issues or experiencing overwhelming thoughts. Megan suggests using a prioritization matrix that combines various approaches. When we find ourselves in a state of panic or anxiety, it's crucial to recognize that it's not a reflection of our intelligence or capabilities. Our brain's chemical reactions during these moments can lead to irrational decision-making. 

Listen to this episode to hear about Megan’s practical exercise that allows us to operate at our highest capacity. This includes a time-limited approach to creating a list and then identifying what truly needs to be done within the next 24 hours and has negative consequences if not addressed. By narrowing down the list to these critical tasks, we can create a focused action plan.

Consulting our calendar, we can determine when to tackle these priority tasks. This approach helps us break free from the overwhelming feeling of urgency by taking a step-by-step approach. By calming our brain, focusing on specific tasks, and creating a plan, we can overcome overwhelm and maintain momentum.

Designing the Perfect Planner: Seeing the Whole Week

When it comes to effective time management, finding the right planner is key. Megan emphasized the importance of using a planner that provides a week-at-a-view layout with hourly slots. This design allows us to see our entire week at a glance, empowering us to assess our available time and commitments. By visualizing the bigger picture, we can strategically plan our days and make informed decisions about our priorities. Having a holistic view of the week enables us to stay organized and focused on what truly matters.

This includes your food. I always talk to my patients about planning the weekly menu. When you do this, you can buy fresh produce and cook in bulk. This saves time and reduces decision fatigue. I also recommend using those daily pill containers for your supplements to keep them straight and streamline the process. 

Planning for Success: Balancing Predictability and Flexibility 

The beauty of weekly planning lies in its ability to strike a balance between predictability and flexibility. By creating a weekly plan, we gain clarity and can allocate dedicated time for important projects and tasks. However, life is full of unexpected changes and challenges. Megan emphasized the need to plan for uncertainty. Whether it's a sudden health issue or a last-minute travel plan, we must be adaptable. Megan's advice was to allocate flexible time blocks or leave room for unexpected events. This approach allows us to manage our time effectively while still being able to adapt to unexpected circumstances.

The To-Don't List: Letting Go of Unnecessary Tasks

One of the most transformative concepts Megan shared was the idea of the to-don't list. It involves identifying tasks that we don't enjoy doing or that can be delegated to others. By starting with these tasks, we can explore creative solutions to eliminate or outsource them. This practice liberates our time and energy, allowing us to focus on what truly matters. It's essential to let go of tasks that don't align with our values or bring us joy. By doing so, we can create more space in our lives for the activities that contribute to our well-being and happiness.

Prioritizing Self-Care: Health and Well-Being First

In our pursuit of productivity and success, we often neglect our own well-being. Megan emphasized the importance of prioritizing self-care and allocating dedicated time for it. Whether it's exercise, healthcare appointments, or practices that support our well-being, our health should always come first. Megan reminded us that it's okay to let some tasks slide temporarily. Just like a new mom focuses on her newborn and lets other things go, we need to prioritize our healing and well-being. When we give ourselves permission to focus on what truly matters, we can navigate life's challenges with more resilience and grace.

The Power of Making Wiser Choices

Mastering time management is about making wiser choices with the limited resource we have: time. By embracing the power of weekly planning, using a planner that suits our needs, planning for uncertainty, and creating a to-don't list, we can find greater balance in our lives. It's essential to prioritize self-care and give ourselves permission to focus on what truly matters. In doing so, we'll experience less stress, greater fulfillment, and the ability to achieve our goals while maintaining our well-being.

To help you implement these insights into your own life, here are some practical tips for effective time management:

1. Start with a planner that provides a week-at-a-view layout with hourly slots. This allows you to see your entire week and allocate time strategically.

The Case: 

• Mira has Hashimoto's and also suffers from digestive issues. 
• These issues are long-standing and doctors or dietary changes have been ineffective
• Researching online has her feeling overwhelmed and lost. 

There’s so much confusing information online and when that is paired with a doctor telling you that there is nothing to be done or that tests show no issues, it leaves many Hashimoto’s patients suffering from gut issues resigned to never feeling good again. That’s why I was so glad that Mira came to me so we could do some real investigating to find the root cause of her digestive issues. 

The Investigation

I turned to a good friend of the Health Mysteries Solved show, Evan Brand. He is a functional medicine doctor and he also has his own podcast, The Evan Brand Show. He’s shared his expertise with us before, if you haven’t listened to episode 6, I encourage you to go back and give it a listen - it was a very eye-opening look at the hidden risks of mold. We discussed mold in this episode as well but I wanted to start our conversation talking about digestive issues for those with hypothyroidism and Hashimoto’s. 

Digestive Issues Triggering Autoimmunity (including Hashimoto’s) May Start in Childhood

We don’t often think about the relationship between our gut health and our immune system but they are incredibly connected. Evan shares that some of these issues start at a very early age. Evan believes it is crucial to address children's gut health as resolving these issues early on may help prevent the development of Hashimoto's and other autoimmune conditions in their teenage and adult years. He specifically points to autoimmune-triggering bacteria such as Klebsiella, Morganella, Strep, Staph, and Pseudomonas, which have been linked to various autoimmune conditions. 

Evan encourages parents to consider gut health as a potential cause for behavioral issues, hyper-sensitivities, attention challenges, or other personality changes that could easily be presumed to be ADHD, OCD, or personality quirks. These could in fact, says Evan, be signs of a bacterial imbalance, parasites, or mold toxicity. He stresses the importance of dealing with these issues early because they can develop into long-term consequences such as anxiety, depression, chronic fatigue, weight issues, sleep problems, behavioral issues, and learning difficulties as they grow older. Evan also notes that dysbiosis, an imbalance of gut bacteria, can occur at a young age, regardless of whether the child was born via C-section or vaginal birth.

Lyme Disease and Babesiosis As Autoimmunity Triggers

Evan also notes that babies can contract Lyme disease through the placenta of an infected mother or directly through a tick bite. He notes that tick bites are a growing problem. 

Evan points to a recent statement from the CDC called Trends in Reported Babesiosis Cases which points to the significant increase in babesiosis cases from 2011 to 2019. Interestingly, he says that if cases go undiagnosed, these issues could be the cause of Hashimoto’s. 

This concept aligns with what we talk about all the time on this show regarding the triggers of Hashimoto’s including bacterial overgrowth, stress, and mold or toxin exposure. Evan explains that addressing these underlying issues often leads to a decrease in antibodies associated with Hashimoto's, highlighting the domino effect of these interconnected health conditions.

Are Hashimoto’s and Autoimmunity a Purely Modern Health Threat

Evan and I discuss how our ancestors may have dealt with these infections and pathogens in the past. While these issues likely existed, they weren't as prevalent due to differences in environmental factors, stress levels, and exposure to chemicals and technology. Our modern lifestyles contribute to chronic inflammation and dysbiosis, leading to the autoimmune misery we see today. It's important to address these root causes, including gut health, to alleviate symptoms and improve overall well-being.

Testing for Hidden Causes of Ill-Health

Diagnosing dysbiosis, infections, and autoimmune diseases requires tests that go beyond what a conventional doctor (or even a gastroenterologist or endocrinologist) will order. Evan suggests combining DNA stool testing with an organic acids test (if budget permits), as it provides a broader picture of gut health and mitochondrial function. These are exactly the tests I recommend to my clients because these advanced tests allow us to uncover underlying infections, dysbiosis, and other issues that may be contributing to autoimmune conditions like Hashimoto's.

Where to Start in Solving Dysbiosis and Other Potential Hashimoto’s Triggers

Comprehensive testing, as mentioned above, is the key to knowing where to start. In most cases, treatment begins with dietary changes, supplements, as well as lifestyle changes. However, even with these actions, if the root cause of the issue is not addressed, the issues will pop back up eventually. This is why it’s so important to find the root cause and address it. 

If gut issues go untreated or under-treated, it can also lead to low energy levels, poor fat metabolism, anxiety, reduced sex drive, and lower self-confidence. This can create stress which further exacerbates the issues. This is why it’s so important to get the tests and treat the root cause, not the symptoms. This is especially true if mold is the root cause. 

The Impact of Mold in Our Homes and on Our Health

Mold is more than just a cosmetic issue; it can have a significant impact on our well-being. Mold spores can trigger allergic reactions, and respiratory issues, and even contribute to chronic conditions. Recognizing the potential health risks associated with mold exposure is the first step toward protecting ourselves and our loved ones.

To test your home for mold, Evan suggests using the petri dish method because it allows you to identify specific rooms in the home where mold issues exist. For example, you may find that the basement has the highest concentration of spores but that your daughter's bedroom is fine. This allows you to treat specific areas and not feel like your entire house is hurting you. This is important because the stress of thinking that your entire house is a threat to your health can have a serious impact on your stress levels which can also impact your thyroid. 

It’s so important to know that mold can be mitigated and the impact of the mold in your home can be managed. Not panicking and dealing with the issues calmly are an important part of staying healthy through this issue. 

In addition, doing stool and urine tests can help you track the impact of mold and the results of removing the mold. 

How to start addressing gut infections and underlying mold

In this episode, we discussed many protocols for addressing bacterial and parasitic infections and gut inflammation. There are many over-the-counter options but ultimately, it’s ideal to work with a holistic practitioner for personalized guidance. 

If you want to take action on your own, Evan suggests using binders as a starting point, considering the prevalence of toxins, chemicals, pesticides, and mold in today's world. He mentions that binders are generally safe and necessary for detoxification but suggests not just using charcoal - a blend of binders is more effective. 

There are many options but he recommends the GI detox. The GI detox is a blend of zeolite, charcoal, silica, pectin, and fulvic or humic acid. Evan explains that this blend effectively binds various toxins. Zeolite, for example, is effective for heavy metals, while the clay component specifically targets a highly estrogenic mycotoxin called Xarelanone, which originates from the mold Fusarium commonly found in water-damaged buildings. Xarelanone can disrupt female hormones, leading to infertility, miscarriages, and fetal abnormalities. The presence of Xarelanone can be detected through a urine test (organic acids test). 

A Caution About Using Probiotics with Hashimoto’s and Histamine Intolerance

Probiotics are also important in dealing with a mold detox. However, many Evan finds that Hashimoto’s patients tend to have histamine-producing bacterial overgrowth, which can contribute to food sensitivities and mast cell issues. For this reason, he utilizes low histamine strains of bacteria in their protocols. He mentions that they now incorporate probiotics right from the beginning, as they have discovered that certain probiotics can actually convert mold into less damaging forms.

Evan mentions a blend called ProBio 50 that he has reviewed with Dr. Tanya Dempsey, an expert in mast cell issues. He explains that according to Dr. Dempsey, Bifidolactis and Lactobacillus Acidophilus, which are included in the blend, are considered low histamine strains. 

On the other hand, he believes that strep strains typically fall into the high histamine category. Evan acknowledges that more research can be done to confirm these categorizations, but he has found success using the ProBio 50 blend with even the most sensitive individuals, as opposed to spore-based products

The Case: 

• Helen has 2 different autoimmune diseases and hypothyroidism and rarely feels good. 
• She was experiencing fatigue, brain fog, body aches, and depression. 
• She wasn’t sure if the depression was a symptom or something caused by her struggles.

The Investigation

When I met Helen, I saw that there were many areas where we could start to intervene. I knew we had to look at her DNA blueprint if we were going to solve this health mystery. There are a lot of different ways that our DNA can inform us about our health but Kashif Khan has a unique approach. I knew he’d be the right person to talk to about Helen’s case.

Thought Leader in Functional Genetics

Kashif  Khan is the author of The DNA Way, a two-time TEDx Speaker and the Founder of The DNA Company, where personalized medicine is being pioneered through unique insights into the human genome. He is also the host of the Unpilled podcast. He knows firsthand the power of understanding your DNA blueprint because he was able to heal his own issues through functional genetics. 

Understanding the Story Our Genes Are Really Telling Us

So many people plagued with health issues blame their genes. What most don’t realize is that our genetic makeup does not completely determine our health. Genes can turn on and off, we can provide detours that will get us to better health outcomes. In my conversation with Kashif, he explains that often, people look at DNA testing as a way to determine the likelihood that they will experience disease. For example, one DNA test might tell you that you have an 80% chance of breast cancer. Kashif feels like the model of DNA testing is broken because the body doesn’t work that way. 

He suggests a more comprehensive approach that requires us to understand the genome properly. We can move from ‘this gene equals this problem’ to ‘this gene informs us how your body functions and the most supportive nutrition and lifestyle choices.’ It’s a much more functional approach to genetics and addresses disease, chronic conditions, and overall health which I really appreciate because it’s so empowering.

Functional Genetics and Autoimmunity (Hashimoto’s)

Helen has 2 autoimmune diseases and has hypothyroidism so I was curious to hear what Kashif had to say about the role that gene expression plays in autoimmune disease. He explained there is a race to identify the autoimmune gene, but the body doesn't work in such a straightforward manner. It's becoming evident, he says, that the underlying system's failure (rather than a single gene) is what leads to autoimmune conditions. 

He shares a powerful example relating to hormone toxicity in women. There is a hormone cascade that involves the production, conversion, and clearance of hormones. If a woman is estrogen dominant and lacks proper detox pathways, exposure to hormone disruptors in the environment or additional estrogen from birth control or hormone therapy can lead to chronic inflammation and eventually manifest as an autoimmune condition or other health issues. The outcome varies among individuals based on their specific hardware failures. This example highlights that, while there may not be a direct gene that causes autoimmunity, understanding the pathways and habits can empower individuals to make informed choices and take preventive measures from a young age.

In other words, gene expression plays a role in autoimmunity but is not 100% of the picture. 

Can Your DNA Impact Gut Health?

When examining our DNA and its relationship with the gut, there are important insights to consider, says Kashif. One significant finding is the impact of specific dietary choices. For example, the growing popularity of veganism has led many individuals to adopt this lifestyle. However, it is crucial to recognize that not everyone possesses the genetic makeup necessary to break down certain plant-based proteins found in beans, lentils, legumes, and chickpeas. Over time, those lacking the required enzyme may experience symptoms resembling an autoimmune condition due to the strain placed on their gut by consuming these protein sources as their primary protein intake. This example illustrates the importance of aligning dietary choices with individual genetic predispositions. The same caution goes out to those following a Keto or carnivore diet - they may initially feel great but after a few weeks, they discover health issues simply because they are not genetically aligned with their diet. 

This is why it’s so powerful to get a map of your genetic makeup because even “healthy eaters” may discover that their misaligned diet plan is the root cause of their health concerns. 

Can Our Genes Cause Brain Fog?

Our genetics play a significant role in our brain health and overall cognitive function. Kashif says individuals may experience symptoms in varying ways due to their unique genetic makeup. For example, some individuals may be more prone to brain fog or joint pain, while others may have different manifestations. 

Mitochondrial health is crucial for brain function, as the brain has the second highest density of mitochondria in the body. Some people may have genetic factors that affect mitochondrial function, making them more susceptible to brain-related symptoms and difficulties. Another genetic factor is a gene called BDNF, which influences neuroplasticity, brain repair, and neurogenesis. Individuals who struggle with efficient neuroplasticity and brain repair may experience greater challenges in handling cognitive loads, with symptoms such as brain fog setting in more quickly and taking longer to recover from. 

Perception is also influenced by genetics, explains Kashif. Individuals may have different neurochemical maps that affect risk aversion, reward-seeking behavior, procrastination, or susceptibility to burnout. On the other hand, some individuals may have fewer dopamine receptors, leading to increased seeking behavior, while others may experience difficulties in experiencing dopamine at appropriate levels. 

Is Autism Genetic?

Considering the role of gene expression in the brain, it made me curious about autism. In the functional medicine world, there are so many thoughts about contributing factors. From exposure to heavy metals to gut microbes, to obesity, autoimmunity and the gut-brain connection. 

Kashif has worked with autistic children and says it’s important, when talking about the cause and support of autism, to distinguish between innate autism (a child is born with the condition), and acquired autism (external factors contribute to its development). He says the allopathic medical perspective tends to view all autism as innate, while the functional medicine approach attributes it to outside exposure. Both perspectives have validity, but they do not account for the entire spectrum of autism. 

He further explains that the first step is to determine which category the child falls into. If it is innate, the focus is on improving brain function and addressing behavioral development issues, as it is not reversible. Functional interventions can still help the child thrive, but the underlying condition remains. Research is ongoing to identify the switch that triggers autism, but it is yet to be discovered. However, a significant portion of autism cases fall into the second category, where a child was initially fine but experienced a change after a specific event. In these cases, inflammation caused by that event or events can lead to brain inflammation and altered development. Understanding the child's unique genetic makeup is essential to determine the appropriate approach. By focusing on the "why" rather than just the condition itself, individualized solutions can be provided for chronic conditions, respecting the diverse factors contributing to each person's health challenges.

Not All Genetic Testing Is Created Equal

Many of us immediately think of tests like 23andMe when we think about getting our genetic testing done. Kashif says there are other options that go much deeper. 

As a listener of this show, you are likely aware that functional medicine offers a distinct approach to healthcare compared to traditional medicine, focusing on understanding the underlying causes of diseases and addressing them rather than just managing symptoms. This approach extends to functional genetics, which looks beyond individual genes and considers the interconnected systems in the body. Functional genomics takes into account factors such as detoxification, methylation, neurology, mood, behavior, and gut health to identify the root of the problem. 

While genetic testing can be valuable for specific genetic conditions, functional genomics is more useful for understanding how the body functions and how lifestyle choices contribute to inflammation, which is often at the core of many health issues. In fact, most major health conditions, including cancer, cardiovascular disease, and neurodegenerative disorders, are rooted in inflammation. By focusing on maintaining healthy cells and addressing inflammation through lifestyle choices, individuals can prioritize their long-term health and potentially prevent chronic diseases. However, in today's environment, with various threats like environmental toxins, poor nutrition, and elevated stress

The Case: 

• Helen has 2 different autoimmune diseases and hypothyroidism and rarely feels good. 
• She was experiencing fatigue, brain fog, body aches, and depression. 
• She wasn’t sure if the depression was a symptom or something caused by her struggles.

The Investigation

When I met Helen, I saw that there were many areas where we could start to intervene. I knew we had to look at her DNA blueprint if we were going to solve this health mystery. There are a lot of different ways that our DNA can inform us about our health but Kashif Khan has a unique approach. I knew he’d be the right person to talk to about Helen’s case.

Thought Leader in Functional Genetics

Kashif  Khan is the author of The DNA Way, a two-time TEDx Speaker and the Founder of The DNA Company, where personalized medicine is being pioneered through unique insights into the human genome. He is also the host of the Unpilled podcast. He knows firsthand the power of understanding your DNA blueprint because he was able to heal his own issues through functional genetics. 

Understanding the Story Our Genes Are Really Telling Us

So many people plagued with health issues blame their genes. What most don’t realize is that our genetic makeup does not completely determine our health. Genes can turn on and off, we can provide detours that will get us to better health outcomes. In my conversation with Kashif, he explains that often, people look at DNA testing as a way to determine the likelihood that they will experience disease. For example, one DNA test might tell you that you have an 80% chance of breast cancer. Kashif feels like the model of DNA testing is broken because the body doesn’t work that way. 

He suggests a more comprehensive approach that requires us to understand the genome properly. We can move from ‘this gene equals this problem’ to ‘this gene informs us how your body functions and the most supportive nutrition and lifestyle choices.’ It’s a much more functional approach to genetics and addresses disease, chronic conditions, and overall health which I really appreciate because it’s so empowering.

Functional Genetics and Autoimmunity (Hashimoto’s)

Helen has 2 autoimmune diseases and has hypothyroidism so I was curious to hear what Kashif had to say about the role that gene expression plays in autoimmune disease. He explained there is a race to identify the autoimmune gene, but the body doesn't work in such a straightforward manner. It's becoming evident, he says, that the underlying system's failure (rather than a single gene) is what leads to autoimmune conditions. 

He shares a powerful example relating to hormone toxicity in women. There is a hormone cascade that involves the production, conversion, and clearance of hormones. If a woman is estrogen dominant and lacks proper detox pathways, exposure to hormone disruptors in the environment or additional estrogen from birth control or hormone therapy can lead to chronic inflammation and eventually manifest as an autoimmune condition or other health issues. The outcome varies among individuals based on their specific hardware failures. This example highlights that, while there may not be a direct gene that causes autoimmunity, understanding the pathways and habits can empower individuals to make informed choices and take preventive measures from a young age.

In other words, gene expression plays a role in autoimmunity but is not 100% of the picture. 

Can Your DNA Impact Gut Health?

When examining our DNA and its relationship with the gut, there are important insights to consider, says Kashif. One significant finding is the impact of specific dietary choices. For example, the growing popularity of veganism has led many individuals to adopt this lifestyle. However, it is crucial to recognize that not everyone possesses the genetic makeup necessary to break down certain plant-based proteins found in beans, lentils, legumes, and chickpeas. Over time, those lacking the required enzyme may experience symptoms resembling an autoimmune condition due to the strain placed on their gut by consuming these protein sources as their primary protein intake. This example illustrates the importance of aligning dietary choices with individual genetic predispositions. The same caution goes out to those following a Keto or carnivore diet - they may initially feel great but after a few weeks, they discover health issues simply because they are not genetically aligned with their diet. 

This is why it’s so powerful to get a map of your genetic makeup because even “healthy eaters” may discover that their misaligned diet plan is the root cause of their health concerns. 

Can Our Genes Cause Brain Fog?

Our genetics play a significant role in our brain health and overall cognitive function. Kashif says individuals may experience symptoms in varying ways due to their unique genetic makeup. For example, some individuals may be more prone to brain fog or joint pain, while others may have different manifestations. 

Mitochondrial health is crucial for brain function, as the brain has the second highest density of mitochondria in the body. Some people may have genetic factors that affect mitochondrial function, making them more susceptible to brain-related symptoms and difficulties. Another genetic factor is a gene called BDNF, which influences neuroplasticity, brain repair, and neurogenesis. Individuals who struggle with efficient neuroplasticity and brain repair may experience greater challenges in handling cognitive loads, with symptoms such as brain fog setting in more quickly and taking longer to recover from. 

Perception is also influenced by genetics, explains Kashif. Individuals may have different neurochemical maps that affect risk aversion, reward-seeking behavior, procrastination, or susceptibility to burnout. On the other hand, some individuals may have fewer dopamine receptors, leading to increased seeking behavior, while others may experience difficulties in experiencing dopamine at appropriate levels. 

Is Autism Genetic?

Considering the role of gene expression in the brain, it made me curious about autism. In the functional medicine world, there are so many thoughts about contributing factors. From exposure to heavy metals to gut microbes, to obesity, autoimmunity and the gut-brain connection. 

Kashif has worked with autistic children and says it’s important, when talking about the cause and support of autism, to distinguish between innate autism (a child is born with the condition), and acquired autism (external factors contribute to its development). He says the allopathic medical perspective tends to view all autism as innate, while the functional medicine approach attributes it to outside exposure. Both perspectives have validity, but they do not account for the entire spectrum of autism. 

He further explains that the first step is to determine which category the child falls into. If it is innate, the focus is on improving brain function and addressing behavioral development issues, as it is not reversible. Functional interventions can still help the child thrive, but the underlying condition remains. Research is ongoing to identify the switch that triggers autism, but it is yet to be discovered. However, a significant portion of autism cases fall into the second category, where a child was initially fine but experienced a change after a specific event. In these cases, inflammation caused by that event or events can lead to brain inflammation and altered development. Understanding the child's unique genetic makeup is essential to determine the appropriate approach. By focusing on the "why" rather than just the condition itself, individualized solutions can be provided for chronic conditions, respecting the diverse factors contributing to each person's health challenges.

Not All Genetic Testing Is Created Equal

Many of us immediately think of tests like 23andMe when we think about getting our genetic testing done. Kashif says there are other options that go much deeper. 

As a listener of this show, you are likely aware that functional medicine offers a distinct approach to healthcare compared to traditional medicine, focusing on understanding the underlying causes of diseases and addressing them rather than just managing symptoms. This approach extends to functional genetics, which looks beyond individual genes and considers the interconnected systems in the body. Functional genomics takes into account factors such as detoxification, methylation, neurology, mood, behavior, and gut health to identify the root of the problem. 

While genetic testing can be valuable for specific genetic conditions, functional genomics is more useful for understanding how the body functions and how lifestyle choices contribute to inflammation, which is often at the core of many health issues. In fact, most major health conditions, including cancer, cardiovascular disease, and neurodegenerative disorders, are rooted in inflammation. By focusing on maintaining healthy cells and addressing inflammation through lifestyle choices, individuals can prioritize their long-term health and potentially prevent chronic diseases. However, in today's environment, with various threats like environmental toxins, poor nutrition, and elevated stress

The Investigation

Back in my 20s, I started to notice that sometimes my brain was just not clear. It might be me forgetting a friend's name or missing an appointment. It happened so often that I started to normalize it. I would shrug it off even when friends pointed it out with concern. When I did bring the issue to my conventional doctor, it was dismissed. 

But, even back then, I knew there was something else going on. I knew that I had to get to the bottom of this health mystery around my brain fog. 

Decades later, I know a lot more about brain fog and in this episode, I want to share 4 of the most common causes of brain fog and what you can do about it. 

Reason #1: Hypothyroidism

Brain fog is closely linked to hypothyroidism, a condition where the thyroid gland doesn't produce enough hormones. This deficiency affects the membranes that support brain function, leading to cognitive difficulties. To overcome brain fog caused by hypothyroidism, it's essential to prioritize thyroid support tailored to your specific needs and, most importantly your thyroid type. If you don’t know your thyroid type, it’s really essential for supporting your thyroid just for you. I will be showing you how to figure this out on June 15th so that instead of feeling stuck, confused and frustrated, you will have clarity and certainty which means you will know exactly what to do to support your thyroid. And ultimately what this really means is that you can finally have peace of mind that you are not alone in your struggles because you will have support from someone who really gets it. Click here to register.

Reason #2: Hashimoto’s Disease

Another primary contributor to brain fog is Hashimoto’s disease because of all of the inflammation that comes along with Hashimoto’s. What happens with Hashimoto’s is that the immune system gets confused and starts to believe the thyroid is a threat. It attacks it but that’s not just bad for the thyroid, it has repercussions throughout the body because the immune system is stuck in attack mode. The brain is one of the areas under attack and as a result, inflammation occurs causing brain fog. 

To combat brain fog associated with Hashimotos, it's crucial to identify and address triggers that contribute to inflammation. Our upcoming training is also helpful for those dealing with Hashimoto’s as it includes in-depth knowledge and effective strategies to help you on your healing journey, empowering you to reclaim mental clarity.

Reason #3: Shifts in Estrogen and Hormonal Balance

Fluctuations in estrogen levels during puberty, pregnancy, postpartum, and menopause can wreak havoc on our cognitive abilities, making it another potential cause of brain fog. This foggy state is particularly evident when estrogen levels drop, resulting in symptoms like "Mommy-brain" after childbirth or during menopause. If you have both Hashimoto’s and hypothyroidism, it's paramount to prioritize support for your thyroid as it directly impacts hormone balance. 

Maintaining hormonal balance is crucial for optimal brain function. Strategies such as stress management, regular exercise, and targeted supplements can support hormone balance and alleviate brain fog related to hormonal fluctuations. You can also explore natural support options like Fem Guard or consider hormone support, as discussed in episode 96 and also episode 110 of Health Mysteries Solved, where we demystify hormones for perimenopause and menopause.

Reason #4: Inflammation and Free Radicals

The fourth major cause of brain fog is the presence of free radicals in the body. Free radicals damage our cells and when the body is inflamed, free radicals are created. Even if the inflammation doesn’t start in the brain, it can travel and spread into the brain and cause brain fog. This is a significant concern for those with Hashimoto’s or other autoimmunity issues but even for people who don't have autoimmunity, the initial inflammation could be caused by exposure to certain toxins, foods, oxidative stress, or other triggers. It's crucial to adopt measures that reduce overall inflammation through lifestyle modifications and dietary choices. By doing so, you can minimize the negative effects on your cognitive abilities and experience improved mental clarity.

Supplements for Brain Fog that Really Work

With decades of experience and exploration in reducing inflammation and the brain fog that comes with it, I’ve discovered a handful of supplements that I like to recommend. As always, please consult your own personal health practitioner before starting a new supplement regimen. Here are the ones I find to be effective: 

1. Annatto E 300 by Designs for Health

Annatto-E 300 is a remarkable brain fog supplement. It contains unique forms of vitamin E that are 50 times stronger than conventional supplements. This potent formulation specifically targets lipid oxidation, which plays a crucial role in maintaining optimal brain function. By incorporating Annatto E 300 into your daily regimen, you can support your brain health and combat brain fog effectively. We offer 10% off any Design for Health products on our website just enter the promo code: DFH10.

1. Biotoxin Binder

Biotoxin Binder is a powerful supplement that combines humic and fulvic acid, known for its ability to bind toxins, chemicals, allergens, and molds. What sets this supplement apart is its compatibility with other supplements and the fact that it can be taken with food. The convenience and efficacy of Biotoxin Binder make it an excellent choice for supporting your brain health and combating brain fog.

1. NeuroFlam

NeuroFlam is a meticulously crafted brain fog supplement that provides a range of potent antioxidants to support optimal brain function. By combating oxidative stress and inflammation, NeuroFlam helps promote cognitive clarity and combat brain fog effectively. Including NeuroFlam in your daily routine can be a valuable step towards regaining mental clarity and banishing brain fog. Please note that you will need to create a free account to purchase this product. (it only takes 3 seconds)

Take Action Against Brain Fog

If you find yourself grappling with brain fog, remember that you are not alone, and there are tangible steps you can take to address it. Understanding the underlying reasons behind your brain fog is the first crucial step toward finding effective solutions. Take a closer look at the four reasons shared in this episode and identify which resonates with you the most. 

As you embark on your path to optimize and balance your thyroid, consider incorporating the recommended supplements into your daily routine. Additionally, make sure to join us at our upcoming training sessions for comprehensive guidance and support on your thyroid or Hashimoto's journey. Our trainings have received rave reviews, and I am confident they will provide the assistance you need to regain control of your health and conquer brain fog.

Links:

Resources Mentioned:

Finally Solve Your Thyroid Mystery - Sign up for the course which starts on June 15, 2023

http://ThyroidMysterySolved.com/summertraining

Suggested Products:

Fem Guard

Annatto-E 300

Biotoxin Binder

NeuroFlam – create an account here to access this product https://completenutritionandwellness.com/shop/apex-energetics-restricted-access

Related Podcast Episodes:

096 Demystifying Hormo

The Case: 

• Laura has thyroid issues causing her to feel overweight and her constantly dry skin made her feel like she was aging too fast.  
• She suspected that her issues might be genetic so she did a DNA test which revealed that she had the MTHFR gene. 
• She tried biohacking; taking high doses of B vitamins and a cocktail of other supplements but nothing got her the results she was looking for. 

Investigation

My suspicions were that her various supplements might not be right for her. I also wanted to take a closer look at her diet and lifestyle. 

Because I suspected that the answers were going to be found at the intersection of genetics, diet, and lifestyle I knew that Dr. Kara Fitzgerald would be the perfect person to consult with since she is an expert in epigenetics, nutrition, and aging. She is the author of two incredible books, Younger You: Reduce Your Bio Age and Live Longer, Better and Better Broths & Healing Tonics: 75 Bone Broth and Vegetarian Broth-Based Recipes for Everyone. 

Unveiling the Power of Epigenetics

We often associate our health, thyroid function, and immune system with genetics and autoimmunity. However, as Dr. Kara explains, it is not our genes alone that determine our level of health, immune system function, or even our age. Instead, it is our epigenetics that play a significant role. I know there's a lot of confusion surrounding this topic, and in this episode, Dr. Kara shed some light on it.

She explains that in the early 2000s, scientists successfully deciphered the human genome. They discovered that we possess a little over 23,000 genes, and many believed that this knowledge would provide a clear roadmap to understanding and treating diseases. However, the reality turned out to be quite different. In over 90% of cases, genes alone do not determine our health outcomes. For most of us, the key lies in how our genes are being turned on and off—a fascinating field known as epigenetics that we’ve covered before in episode 143.

Unleashing the Potential of Epigenetic Expression

Epigenetics emerged as a prominent field of study after the completion of the Human Genome Project. It explores the factors that influence gene expression, such as our diet, exposure to toxins, stress levels, social connections, and exercise habits. Simply put, we have the power to determine which genes are activated and which ones remain dormant. Ideally, we want to activate the genes associated with health, longevity, and overall well-being while silencing those that contribute to disease progression.

This realization is particularly empowering for individuals like Laura, who believed that her family history of Hashimoto's meant she was destined to follow the same path. However, epigenetics shows us that we are not bound by our genetic heritage alone. 

Lifestyle and Nutrition: The Epigenetic Keys

Dr. Kara dives into the exciting realm of lifestyle and nutrition, revealing some of the most significant factors that influence gene expression. Understanding these keys can help us unlock the potential for anti-aging, detoxification, and disease prevention.

1. Diet Program: Dr. Kara shares insights from a groundbreaking study on biological aging, which focused on DNA methylation—a marker of aging and gene expression changes. The study participants followed a specific diet program designed to optimize gene expression. The key elements of this diet program include:

• Veggies and Greens: Emphasizing a plant-rich diet with an abundance of greens and cruciferous vegetables, cooked to support thyroid health.
• Low-Glycemic and Fruit-Dense: Opting for low-glycemic vegetables and incorporating dark berries rich in polyphenols.
• Smart Protein Choices: Eggs and liver (if open to consuming them) are excellent gene whispering foods, while seeds, nuts, and fatty fish provide essential nutrients.
• Healthy Oils: Including extra virgin olive oil and coconut oil in cooking.
• Vitamin D and Mushrooms: Ensuring sufficient vitamin D intake and recognizing the gene-regulating properties of mushrooms, such as shiitake and maitake.

2. Herbs and Spices: Dr. Kara highlights the impact of polyphenols found in various herbs and spices. Rosemary, thyme, oregano, curcumin, turmeric, quercetin, and resveratrol are just a few examples of potent gene regulators.

It's important to note that while we may inherit some gene expression patterns from our parents and ancestors, we still hold the reins and have the power to influence our health destiny. Understanding this gives us the opportunity to make informed choices and take control of our well-being.

Dr. Kara emphasizes the vital connection between epigenetics, aging, and thyroid disease. Aging acts as a primary driver for various chronic conditions, including hypothyroidism, Graves' disease, and subclinical hypothyroidism. Exploring the changes in epigenetic expression and DNA methylation provides valuable insights into the underlying mechanisms of these conditions.

Epigenetic Lifestyle: A Holistic Approach to Optimal Health

Dr. Kara uses her study and others as examples to showcase that it's not just about individual foods but a synergistic combination that maximizes the effects on gene expression. She explains that her program incorporates low glycemic choices, intermittent fasting, exercise, and other crucial lifestyle factors.

The Power of Simple Lifestyle Changes

Dr. Kara says the key to success is by making simple, doable lifestyle changes to improve our health and slow down the aging process. She emphasizes that the goal is not to engage in extreme measures but rather to focus on sustainable habits that can positively impact our overall well-being. That was the motivation behind her research team’s design of a program called "Younger You" that aimed to create meaningful changes in participants' health. The program included a simple exercise prescription, prioritized quality sleep, incorporated basic meditation practices, and recommended the use of a greens powder and probiotic supplement.

The results she shared were truly astonishing to me. 

Understanding the Role of DNA Methylation

DNA methylation plays a crucial role in gene expression and epigenetics. We’ve talked about this before (on this episode about the MTHFR gene) but it’s important to go beyond that. Methylation is involved in numerous essential processes in the body, from metabolizing hormones and neurotransmitters to maintaining optimal cell function. Methylation is influenced by various factors, including nutrients, gut health, and the microbiome.

Comprehensive testing is needed to assess methylation status and overall metabolic function. This involves looking at biomarkers such as homocysteine and methylation cycle intermediates. A functional medicine approach goes beyond the methylation cycle and explores other metabolic aspects, including gut health and individual nutrient needs. By understanding each person's unique metabolic profile, personalized interventions can be implemented to optimize health and well-being.

However, before diving deeper into methylation, Dr. Kara offered a bit of a caveat: it’s important not to focus too much on genetics as it can cause anxiety. Dr. Kara says that our genes do not determine our destiny. Other tests, such as the organic acid test can help us paint a bigger picture of what’s going on and allow us to use a more holistic approach to solving health mysteries. 

DNA Methylation and Disease Risk

There are two things to consider with methylation: overmethylation (hypermethylation) and undermethylation (hypomethylation). However, Dr. Kara clarified that these are not necessarily the phenomena that regulate gene expression through epigenetics and DNA methylation. Methylation patterns can be complex, and it is crucial to consider the context and specific genes involved.

Dr. Kara says her study demonstrates that lifestyle interventions, particularly dietary changes, can positively influence DNA methylation patterns. Contrary to the popular belief of simply increasing methylation, it is about directing the methylation process to beneficial areas. She emphasizes the role of exercise, sleep, stress management, and toxin avoidance as critical epi nutrients that regulate DNA methylation. These lifestyle factors work in harmony with dietary interventions to support optimal methylation.

The study's outcomes highlight the body's remarkable ability to heal and rebalance when provided with the rig

The Case: 

• Mindy has Hashimoto’s and hypothyroidism and experiences low energy and anxiety
• She’s worried genetics may be making it worse because her mother also has Hashimoto’s
• She’s feeling like the genetic cards are stacked against her and there’s nothing she can do to feel healthy again. 

The Investigation

When I first met Mindy, I noted the stock she was placing on her genetics, missing things under her control. Genetics are important but they only account for 15% of our wellness picture. I knew that there were a myriad of things we could do to shift the impact of her genetics on her health. However, I also knew that a bigger shift might be needed at the epigenetic level.  

The Epigenetic Expert - Anat Peri

To look further into what might be going on for Mindy, I invited Anat Peri back to the show. Longtime listeners may remember her from episode 55 of Health Mysteries Solved when she shared her insights on emotional resilience. I highly recommend going back and listening to (or relistening to) that episode. Anat is an inner child expert and the founder of Training Camp for the Soul. She has 18 years of experience as a trauma-informed coach using a variety of tools including mindset, somatic healing, safety connection, nervous system regulation, and inner child reparenting. Through her work, she has learned a great deal about epigenetics and how our upbringing can manifest physically in our adult minds and our health.  

What is Epigenetics?

Epigenetics refers to the biology of our beliefs and how we view the world. It's about how our reactions to life impact our nervous system and whether we operate in a parasympathetic state or a stressful (sympathetic) state. This can have a huge impact on our health, as stress and trauma can lead to a range of health issues and can be a major trigger for Hashimoto’s. 

Anat explains that everything we learn as children is learned from our caretakers, and if they were absent or dysfunctional, we may have learned unhealthy patterns that can impact our health as adults. Anat explains that we learn so much at a young age because as children we are like sponges; soaking up what we see, hear, and feel energetically from our caretakers. Our beliefs and the way we view the world are formed at a young age, and they can have a huge impact on our health later on. Often, we are completely unaware of the role epigenetics is playing in our health.

The good news is that we can turn our epigenetics on and off, just like gene expressions. Our ability to control our epigenetics depends on our beliefs, how we regulate our nervous system, and how we speak to ourselves. 

Inflammation and its Impact on Health

Inflammation is a natural response of the immune system to injury or infection. However, chronic inflammation can contribute to a wide range of health issues, including autoimmune diseases such as Hashimoto's and thyroid issues. In my practice, I’ve seen how specific beliefs and behaviors can contribute to inflammation in the body.

Beliefs and Behaviors that Impact Inflammation and Hashimoto’s

One of the beliefs that can increase inflammation is shame. Anat explains that shame is a powerful enough emotion that it can cause us to close in on ourselves and hide our true selves. When we feel ashamed, we may try to suppress our emotions and our needs, which can lead to chronic stress and inflammation.

Fear is another powerful emotion that can contribute to inflammation, says Anat. When we are in a state of fear, our bodies release stress hormones, such as cortisol and adrenaline. Over time, chronic stress can lead to inflammation in the body.

Our parents may have ingrained shame and fear responses into us at a very young age without realizing it. Growing up in a chaotic or turbulent environment can also contribute to inflammation. When our nervous system is constantly activated by stress and fear, our bodies release stress hormones, which can lead to inflammation over time.

The Potential Role of Fathers in the Development of Autoimmune Diseases

In this episode, we really got personal. I looked at the roles my mother and father played in my life. I shared that I felt like my father was always there for me but he didn't necessarily stand up for me when my mother wanted me to do things I didn't want to do, like playing the piano. This experience taught me that my feelings didn't matter and that I had to do what others wanted me to do. I realize now that this is how I was trained to be a people pleaser. Anat was able to relate that to having a lack of boundaries as well as self-rejection and self-abandonment and the connection to my Hashimoto’s. It’s really fascinating.

Anat expanded the discussion further by explaining how fathers can impact the development of autoimmune diseases. She notes that fathers can influence the development of autoimmune diseases by being emotionally unavailable, neglectful, or critical. Children who grow up with fathers who are emotionally unavailable may feel rejected and develop feelings of low self-worth, which can trigger the onset of autoimmune diseases.

We also talk about how fathers can influence the development of autoimmune diseases by modeling certain behaviors. For example, if a father is always putting others' needs before his own, his children may learn that it's not okay to prioritize their own needs.

This is why it’s so important to have a healthy relationship with both parents to reduce the risk of developing autoimmune diseases. It's crucial for fathers to be emotionally available and supportive of their children's feelings and needs. It’s also important for fathers to model healthy behaviors, such as setting boundaries and prioritizing self-care, to help their children develop a healthy attitude towards themselves and others.

Techniques to Connect with Your Inner Child and Begin the Healing Process

Regardless of our relationship with our fathers and how it may have impacted our health, it is possible to change it now. Anat says this is possible by connecting with our inner child. This allows us to identify our emotions, feelings, beliefs, and desires as they relate to our health issues. She suggests grabbing a journal or a piece of paper and writing down everything we feel triggered, upset, frustrated, or stuck about. 

Alternatively, we can record ourselves talking as if we are calling our best friend who listens to us without judging. Once we have our thoughts and emotions recorded, we can identify our inner child's voice by looking for statements that begin with "I feel" or "I want." This practice helps us weed out our inner critic, ego, and shadow, which can hinder our ability to connect with our true feelings and desires.

Anat says it’s important to make sure that we are truly hearing our inner child’s voice because it’s generally not the loudest. Often, our inner critic, ego, and shadow are much more overbearing. She explains that statements that begin with "I am," "I'm upset," "I'm angry," "I feel like he doesn't listen to me," "I feel like I'm being left behind," or "I'm all alone" represent our inner child's voice. On the other hand, statements that contain "I should," "I must," or "I have to" reflect our inner critic. Meanwhile, statements that blame others and avoid taking responsibility for our feelings are the product of our ego. Finally, statements that contain shame, fear, and guilt reflect our shadow.

By identifying our inner child's voice and distinguishing it from our inner critic, ego, and shadow, we can begin the healing process. Connecting with our emotions and desires is crucial to understanding ourselves and our experiences fully. It also helps us identify limiting beliefs that hold us back from living fulfilling lives. Anat Peri emphasizes the importance of being willing to look inward and confront our internal world. This practice can help us shift our focus from external factors to our internal landscape, which is where true healing begins.

Scanning and Embracing Sensations in Our Body

We discuss many ways to create a transformation through connecting with the inner child (and the challenges that many face doing this). One of the keys to making that connection, according to Anat, is to embrace the sensations of the body because sensations are the language of the nervous system. So, when we can learn to be with sensations and name sensations, we speak to the nervous system, and the nervous system can respond and adjust accordingly. She says that we normally put our feelings into two buckets, good feelings, and bad feelings. We label them as happy or scared or anxious, but the opportunity is to go one layer deeper, where we can identify the sensations at the root of these emotions.

The following are the steps to scan and embrace sensations in our body:

Step 1: Take a Deep Breath

To start, take a deep breath and exhale all the stagnant air out of your mouth. Then take a deep breath, filling up the whole body deep into the belly, feeling it expand. Continue to take deep breaths from the belly while sitting in a way that feels supported.

Step 2: Connect with Your Body

Next, connect with your body. Feel the weight of your feet on the ground, the support of the chair or couch, and the sensation of your clothes against your skin.

The Investigation

Those of you who have been listening to the show for a while might remember the challenges I had with coloring my hair during the pandemic. This upset to my regular routine led me to seek out a healthy, at home option. I was particularly curious about how dying my hair may have impacted the management of my Hashimoto’s. You can hear more about that in Episode 121. 

Well, it’s been a year since then and I wanted to give you an update. In this episode, I deep dive into the problem with hair dye for people with autoimmunity, Hashimoto’s and thyroid issues. Plus, I share my review of Hairprint after one year of continuous use. 

The Problem with Traditional Hair Dyes for Autoimmunity and Hypothyroidism

Chemicals in hair dye act as immune triggers. This can be a big issue for anyone with an autoimmune disease like Hashimoto’s because the immune system is already confused and attacking the thyroid. More confusion means more attacks which can result in a flare up or subtle symptom shifts.

If you have hypothyroidism, you may already be dealing with:

• Hair loss
• Thinning hair
• Dry brittle hair
• Frizzy hair

Unfortunately, using traditional hair dye can make it worse. 

Traditional hair dyes use harsh chemicals like ammonia or nanolumens to break apart the layers of the hair protein to give the dye access to the hair shaft. Even ammonia-free dyes use chemicals like Paraphenylenediamine (PPD) that are potentially harmful (they’re even banned in Canada and the EU). Moreover, chemicals in hair dyes seep into the bloodstream during the dying process, causing harm to the immune system, respiratory system, liver, kidneys, and can trigger serious allergic reactions, hair loss, and hair breakage.

Why You May Want to Avoid the ‘Organic Hair Dyes’

The term ‘organic’ is not defined, recognized, or regulated by the FDA in the personal care industry. Companies can add natural ingredients and call their hair dyes organic or natural, but it doesn't mean that they're chemical-free. 

Often, the added botanical or organic elements have nothing to do with the dyeing process and are there in addition to all the usual chemicals that are in conventional hair dye. It might just be a marketing gimmick.

Hairprint: A Safer Alternative to Traditional Hair Dye?

I was thrilled to find Hairprint last year for all of the reasons I listed above. Before I share more about the product, I want to clarify that this is not a sponsored post - I genuinely use the product and love the product. And, in the past year of using it, I’ve learned a lot about how to get the best results. 

First, let me share a bit about Hairprint (in case you missed episode 121). It’s a unique product that doesn't break up the hair follicle and degrade it in any way, unlike traditional hair dyes. This makes it a safer alternative for everyone but especially for those with thyroid issues or autoimmune diseases. It actually restores the natural pigment in hair without using harsh chemicals. 

How to Apply Hairprint (and Get the Most Out of It)

If you've been using Hairprint or plan to use it, it's important to note that it can have a slight drying effect on your hair, even though protein is great for hair. To combat this, I highly recommend hair oiling. You can use moisturizing oils such as amla oil, argan oil, or jojoba oil. You can apply the oil to the full length of your hair or just the ends depending on where you need it and if you want to avoid adding oil to an oily scalp. Now, if you have a dry scalp, you can apply it there as well. Apply the oil 15-20 minutes before shampooing, or even better, leave it in overnight and wash your hair in the morning. 

I have noticed a significant improvement in my hair's manageability and moisture since starting this practice. I apply the oils right after I do my Hairprint application and then once a week, or sometimes twice a week if I have time. This has made such a difference for my hair, and I highly recommend it for anyone with dry hair, whether or not you are using Hairprint.

Guilt Free Hair Coloring

One of the great things about using Hairprint is that it's natural, so you don't have to feel guilty about coloring your hair more often. You can do it at home without spending a lot of money or spending time traveling to a salon. It's empowering to be your own self-advocate and take control of your hair health. 

My Final Take on Hairprint

By now, you can tell that I love it. If you have been hesitant to try Hairprint, I encourage you to give it a try and take care of your hair naturally.

Eliminating Health Mysteries

If changing how you color your hair can reduce your exposure to toxins, it might just be what you need to shift the scales and help you solve your own health mystery. If you think this episode could be helpful to someone you love, please share it. 

Links:

https://www.myhairprint.com/

Related Podcast Episodes:

10 Reasons Your Hair is Falling Out w/ Deb Matthew

139 How to Power Up Your Hashimoto’s and Thyroid Healing Journey with Hypnosis Part 1

[Ask Inna] Answers to All Your Hashimoto’s Questions

[Ask Inna] More Answers to Your Hashimoto’s Questions (Part 2)

Thanks for Listening

If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information.

Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show!

Find out more at http://healthmysteriessolved.com

PLEASE NOTE

All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider.

Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses.

The Case: 

• Hadley has been struggling with weight loss for years and is now in perimenopause.

• She’s tried many diets but the results were temporary.

• She eats mindfully avoiding gluten, processed foods, and sugar.

• She was intrigued by the hype around Ozempic (semaglutide) but wanted to make sure it was safe and that there weren’t other issues at play in her weight mystery.

Weight Loss Struggles and Hormone Changes in Perimenopause

Hadley’s struggle is so common. Perhaps it’s familiar to you too? You hear about the latest trend in weight loss and wonder (hope) that it’s going to be what helps you get your metabolism working in your favor so you can drop those last few pounds and keep them off. Ozempic has put semaglutide in the news with so many people talking about its popular side effect of weight loss with ease. But, like Hadley, you may have wondered - is it safe and does semaglutide really work for weight loss? 

The Functional Medicine View of Ozempic for Weight Loss

Emily Sadri is a long-time friend of the show. She joined us on episode 107 to share all kinds of eye-opening information about birth control pills and thyroid. 

Because of that informative episode, I knew she was just the person to talk to about Hadley’s case and this trend of using semaglutide for weight loss purposes.

Emily is a board-certified Women's Health Nurse Practitioner, and hormone and weight loss expert. She owns and operates a boutique women’s functional medicine practice in Cleveland, Ohio, and helps women everywhere live more balanced, healthier lives.

What is Semaglutide (originally marketed as Ozempic)?

Semaglutide is a peptide drug that was initially marketed as a medication for diabetes. Developed by Novo Nordisk in 2012, semaglutide was later found to have the potential for weight loss. The drug is now available under the commercial name Wegovy and is prescribed for obesity.

How does Semaglutide Work?

One of the most impressive things about semaglutide is its multi-faceted approach to weight loss. Unlike many weight loss medications that rely on appetite suppression or stimulants, semaglutide works by slowing down digestion and promoting a feeling of fullness.

In this episode, Emily explains that by slowing gastric emptying, semaglutide delays the movement of food from the stomach into the small intestines, which helps to control appetite and reduce food intake. The drug also acts on the hypothalamus, a part of the brain that regulates signaling for many different functions.

The hypothalamus controls sympathetic nervous system signaling, and semaglutide modulates and increases sympathetic output just enough to stimulate lipolysis or fat breakdown. This action raises people's basal metabolic rate slightly, which over time results in weight loss.

What did the Clinical Studies on Semaglutide Find?

Clinical studies have shown that people treated with semaglutide for weight loss have an average of 15% body weight loss, which is a remarkable achievement. This weight loss was achieved without significant lifestyle or diet counseling, making semaglutide seem like exactly what the weight loss market has been waiting for. 

But…

As a practitioner who primarily works with women aged 35 to 55 who often have a thyroid issue or Hashimoto’s, I'm sensitive to anything that stimulates stress pathways. Emily agrees with my caution but says semaglutide is an appealing option for women who are looking to lose weight but want to avoid the side effects of stimulant-based medications. Unlike stimulants, semaglutide doesn't suppress appetite in the same way, which is better for metabolism in the long term. However, sustainable weight loss isn’t just about eating less. 

Exploring the Emotional Component of Weight Loss

In this episode, we also discussed the emotional component of weight loss and how important it is to acknowledge and address it. We talked about how people need reassurance to feel confident about the weight loss process and how feedback can be a useful tool in achieving success.

She explained that extreme dieting can be deleterious for hormones, create stress, and cause women to feel like nothing will work. She emphasized that restoring balance is crucial and shared how semaglutide, can help stabilize glucose levels and create a sense of evenness, reducing anxiety around blood sugar irregularities.

Understanding Semaglutide and Its Effects on Glucose Levels

Semaglutide works for type II diabetes because it raises insulin initially, which is contrary to anti-insulin theories. However, it also helps lower glucose levels. Stabilizing glucose levels can help women overcome the glucose rollercoaster that they often experience. When glucose levels stabilize, the anxiety and chemical dips in blood sugar that drive hunger disappear; leading to a sense of zen detachment from food.

The Role of GLP-1 in Weight Loss

GLP-1 is a peptide hormone that signals satiety and fullness, which helps with weight loss. When we produce more GLP-1, it increases our sensitivity to leptin, our satiety hormone. Emily points out that we don't fully understand why some hormone signals get messed up along the way, but it's likely due to the abundance of food we have access to all the time. This abundance makes us eat as much as we can get our hands on, which causes us to ‘save up for a rainy day’ that doesn't come in modern America. It's one of the main drivers of the obesity epidemic, according to one theory.

Using Semaglutide is Not a Silver Bullet

After our in-depth discussion about using semaglutide for weight loss purposes, Emily cautioned that it's not a silver bullet. While it can provide significant support, she emphasizes the importance of also adopting lifestyle changes, such as reducing processed foods and sugar, and increasing healthy fats and proteins. It's also important to find a sustainable way of eating that works for you and creates balance. She reminds us that weight loss is not just about looking good but about metabolic health, longevity, and overall well-being.

Is Semaglutide for Weight Management a Long-Term or Short-Term Solution?

As a weight management medication, semaglutide was designed to be a long-term solution. But from the perspective of functional medicine, Emily explains, it is important to look at transitioning off the medication or moving to a small maintenance dose that may not even need to be given weekly. The goal is to promote healthy metabolic flexibility and the ability to burn fat easily, which can be achieved by working on all the other things that support weight loss and good health.

What You Need to Know about Taking Semaglutide for Weight Loss

Before jumping on the Ozempic bandwagon, here are the key things you need to know about semaglutide:

1. Side Effects of Semaglutide

Generally, semaglutide is given as a weekly injection and is titrated slowly from a quarter of a milligram to the target dose of 2.4 milligrams to avoid side effects. The primary side effects that people experience are nausea, reduced appetite, anorexia, and initial fatigue. However, these side effects are usually transient, and most people can tolerate them well. Some people are more sensitive to the gastric peptides that the medication increases than others, which can cause nausea, stomach pain, or a feeling of being sick.

1. How Long to Take Semaglutide

Emily explains that typically, people are on Semaglutide for at least nine to twelve months, depending on how much weight they want to lose. The medication is used to support weight loss until the optimal weight is achieved. During the first three to six months, gentle interventions such as improving diet, gut health, and hormone balance are implemented. After six months, people usually start to feel better, have more energy, and are almost at their weight loss goal.

1. Negative Side Effects 

While Semaglutide does increase lipolysis, it can also cause loss of muscle mass, which is concerning, especially for older people who naturally lose muscle as they age. Therefore, it is crucial to preserve and build muscle by eating enough protein and engaging in a rigorous strength training regimen. Muscle is essential for metabolic balance, as it takes up glucose, and losing muscle mass can lead to metabolic dysfunction. To preserve muscle, enough protein must be eaten, and to gain lean body mass, a different metabolic profile must be achieved.

1. Get Professional Support

There is a lot of misinformation out there about semaglutide so it’s imperative that anyone using this drug for weight loss be under the supervision of a professional,

The Case: 

In the last episode, we met Liana and heard all about her issues with fatigue, digestion, hair loss, joint pain, and lack of concentration. As a person living with Hashimoto’s, she knows many of these symptoms are related but was struggling to stick to the healthy routines that could make a difference. 

That’s why I decided to discuss her case with Hypnotherapy expert, Grace Smith. 

In episode 139 of Health Mysteries Solved: Thyroid and Hashimoto’s Revealed, Grace busted the misconceptions surrounding hypnotherapy and explained so clearly how it works. I encourage you to jump back and listen to that episode before proceeding to learn how hypnotherapy can specifically help those with Hashimoto’s and how it helped Liana with her issues.

Stress as a Trigger for Hashimoto’s

There are four main triggers for Hashimoto’s:

1. Food
2. Infection 
3. Toxins (environmental and food)
4. Stress

Of these, stress is so often overlooked. And one of the causes of stress that is easy to overlook because we may not be fully aware of is past trauma. This is where hypnosis can play a big role. 

Sometimes it could be big T trauma (a specific event that is easily identifiable as the source of trauma), but for others, it could even be smaller things. For example, it could be that they may have been rejected from something, or that they struggle with self-worth because of their upbringing. There's also a really big connection between shame and Hashimoto’s and inflammation in general. These small t traumas or limiting beliefs can be the stress trigger for Hashimoto’s without people realizing it.

Grace explains that many of these issues develop in the subconscious before the age of 7. What’s significant about this is that the brain has not yet started to produce beta waves. And so, from seven and under, we're almost completely in the hypnotic state. This is why kids learn so quickly - our brains can easily absorb new information and make new neural pathways in the hypnotic state. However, those neural pathways and ideas we are taught at an early age, tend to stick. This is why it can be hard to change our way of thinking - especially if our brains are stuck in a beta brain state. 

Rewriting Childhood Neural Pathways

Since many of our beliefs (limiting and otherwise) are created before the age of 7, hypnosis can help to take us back to that time and allow us to understand where these ideas come from and rewrite those neural pathways. 

Grace shares a great example of this in our conversation where she’s talking about a kindergarten teacher picking on someone’s drawing and how that can lead to them feeling shame, unworthiness, or even fear of being the center of attention. 

As kids, we have a reaction to that and it’s hard to believe that a single event can affect us years later but Grace says it can be the cause. The good news, she says, is that through hypnosis, you can go back and rewrite that script. And, by doing that, you shift those long-held beliefs and feelings. 

Subconscious Self-Sabotage

When we looked at Liana’s case, we discovered that she had this subconscious belief that she was not worthy of good health. As a result, she couldn’t trust that feeling good would last or that it was really how she felt. That’s why she couldn’t stick with a routine - she never believed it would work, and when it started to, she couldn’t believe it would last. She didn’t think she deserved to be healthy. 

Grace says this is so common and something that can absolutely be addressed through hypnosis.

She shares a great story about a grandmother in her late 70s who was dealing with chronic pain. Doctors and their tests could find no cause. Through hypnosis, Grace was able to get the patient into the theta brainwave state and have a conversation with the woman’s subconscious. It was here that the real cause of the pain was revealed - the woman was afraid to heal because she believed that her family visited her only because she was sick and that if she was healthy, they would not visit as frequently. 

In this episode, Grace reveals how she was able to rewrite this belief and have the woman come out of hypnosis no longer debilitated by pain. 

What Does Hypnosis Feel Like?

Everyone is going to experience being in the theta brainwave state differently. Grace is quick to dismiss the ‘Hollywood’ version of hypnosis where you’re watching a movie on the inside of your eyelids. She explains that some people are more auditory while others are more kinesthetic. It’s important for anyone curious about hypnosis to keep this in mind because they may go in expecting to see something when they can simply know it or feel it and still have it be effective. 

When people don’t have the ‘Hollywood’ experience of being able to visualize, they can sometimes question the validity of the work. It can lead to them not believing in hypnosis. Grace says this is okay because belief is not required. The results will come whether you believe it or not. 

Free Sample Hypnotherapy Session

Because I know people are curious about the experience of hypnotherapy, I asked Grace to help you get into the theta brainwave state. In this episode, she walks you through a simple exercise - be sure to listen in a comfortable position (and that you’re not driving or walking while doing it!)

The exercise shows how effective moving into a theta brainwave state can be for reducing stress levels. Be sure to note your stress level before the exercise and then again after. 

This is a 5-minute exercise and most hypnotherapy sessions done by Grace or her team are 45 minutes, so this really is just a little sample of what it’s like to experience hypnotherapy. 

Grace also has an App where you can continue exploring the benefits of hypnotherapy. 

Conclusion 

Taking a look at what Lianna was doing to support her thyroid, I discovered that she wasn’t clear on her thyroid type. Her thyroid type is ‘unavailable thyroid type’ which means that her thyroid was functioning but her body was unable to absorb the T3 and T4 she was producing. We were able to improve that by supporting her estrogen levels and also addressing her stress. 

But, much of her stress was coming from her limiting beliefs so I knew that hypnosis would help. She was game! She discovered through hypnosis that she had a subconscious belief that nobody feels good and that suffering is part of life. No wonder she didn’t feel like she deserved to be healthy!

Through hypnosis, she was able to rewrite these beliefs and as a result she experienced a reduction in the pain in her joints and she had more energy. She also saw a reduction in hair loss which I think was a result of the shifts in her biochemistry as well as the hypnotherapy sessions and the self-hypnosis she is now doing.

Personal Update

I hope you enjoyed this conversation about hypnosis. I personally have been doing hypnotherapy and have had some major breakthroughs. In fact, I loved the process so much that I am getting my certification for hypnosis as well.  Don’t worry, I’ll still be here as your guide on your Hashimoto’s or thyroid journey - I’ll just have one more tool on my belt! For me, it’s all about getting to the root of the problem so we can heal and enjoy life. And hypnotherapy is definitely one of  the ways to get to that root. I’ll keep you posted on my progress. 

But remember, when it comes to your health issues, the answers really are out there. It's just a matter of looking in the right place and finding the right support. 

Links:

Resources mentioned

Thanks to my guest Grace Smith. You can connect with her and download her app at GetGrace.com.

And you can check out her books, too: 

• Close Your Eyes, Get Free 
• Close Your Eyes, Lose Weight 
• Close Your Eyes, Sleep 
• The Adventures of Sleep (a children’s book)

Related Podcast Episodes:

139 How to Power Up Your Hashimoto’s and Thyroid Healing Journey with Hypnosis Part 1